A desmosome is a type of cell junction found in epithelial and muscle tissue cells. A junction is a structure found in cells that allows connection and communication between cells.

In desmosomes, these junctions have the function of connecting cells together and maintaining the stability and structural integrity of tissues. Desmosomes are composed of two protein plates called desmoplasts, which are found on the outside of cells and are linked by filaments called desmomers.

The demomers extend through the cytoplasmic plate of each cell and attach to other proteins, called intermediate filaments, found in the cytoplasm. This protein system forms a kind of bridge between cells, allowing their connection and maintaining tissue stability.

In addition to their function in the connection and stability of tissues, desmosomes may also play a role in the transmission of signals between cells and in the organization of cytoskeleton filaments in cells. In summary, the main function of desmosomes is to maintain the integrity and structural stability of tissues, although they may also have other roles in the cell.

Relation to aesthetics

In general, tissues in good condition contribute to a person’s aesthetic appearance, as they affect the way the skin and other organs look, but desmosomes are not a direct element in this.

It is possible that some aesthetic treatments, such as skin rejuvenation, can improve the appearance and structure of tissues, but this does not necessarily imply a direct action on desmosomes.

Commitment to quality

This text on desmosomes was written by professional editors and reviewed by Sisneo’s medical-aesthetic team. In addition, we have relied on experts in medicine, engineering and aesthetics as a source of information, as well as specific studies to maintain the quality of what we publish.

At Sisneo Bioscience we are committed to publish truthful and contrasted information. And to update or correct it as soon as new knowledge becomes available.

Among others, we have used the following references:

  • Emmanuella Delva, Dana K. Tucker y Andrew P. Kowalczyk «The Desmosome» en Cold Spring Harbor Perspectives in Biology. doi: 10.1101/cshperspect.a002543.
  • Kowalczyk AP, Green KJ. «Structure, function, and regulation of desmosomes» en Prog Mol Biol Transl Sci. 2013;116:95-118. doi: 10.1016/B978-0-12-394311-8.00005-4.