Hesperidin methyl chalcone

Hesperidin methyl chalcone (HMC) is a compound with a long name and a discreet appearance, but with an interesting history and very specific applications in health and cosmetics. It is a derivative of hesperidin, a natural flavonoid widely studied for its benefits on circulation and vascular protection.

Origin of hesperidin methyl chalcone

Hesperidin is naturally found in citrus fruits, especially in the peel and the white inner part of oranges, lemons, and mandarins. It is one of the compounds responsible for many of the antioxidant properties attributed to these fruits. Hesperidin methyl chalcone does not occur as such in nature. It is the result of a controlled chemical modification of the original hesperidin. This process significantly improves its water solubility, making it easier to absorb and suitable for use in pharmaceutical and cosmetic products. In other words, science takes a good natural compound and makes it more practical.

What is hesperidin methyl chalcone used for?

The main use of hesperidin methyl chalcone is related to vascular and capillary health. Its most common applications include:

• Improvement of microcirculation: helps strengthen capillaries and reduce their fragility.
• Strengthens capillaries and reduces their permeability, which limits fluid leakage that can cause vascular dark circles or under-eye bags.
• Reduction of edema and swelling: especially in tired legs or those with circulatory problems. Support in chronic venous insufficiency, varicose veins, and hemorrhoids.
• Cosmetic use, especially in eye contour products, where it is used to:
  • Reduce under-eye bags
  • Attenuate vascular dark circles
  • Improve the appearance of thin and sensitive skin

Its action is due to the fact that it reinforces the walls of blood vessels, reduces capillary permeability, and exerts an antioxidant effect that protects tissues. HMC acts by modulating mild inflammatory processes and improving venous return. In addition, its antioxidant capacity helps neutralize free radicals, making it an ally at both a functional and aesthetic level. Thanks to its modified form, the body can take advantage of it better than classic hesperidin, which is key for it to be truly effective.

What do we use it for at Sisneo?

At Sisneo Bioscience, we use hesperidin methyl chalcone within the cosmetic active Eyeliss®, an aqueous functional complex specifically designed to address signs of fatigue and aging in the periocular area. Above all, we aim to act against under-eye bags, vascular dark circles, and loss of firmness and tone. By using it within Eyeliss and combining it with techniques such as transdermal electroporation, we make the most of its properties to decongest, firm, and revitalize the eye contour, offering a professional treatment that goes beyond superficial skin care.

Electroporation

Eyeliss

Firmness