What is Sepitonic® M3?

Sepitonic® M3 is an energizing cosmetic active ingredient developed by the French company Seppic. It is a chelated multimineral complex composed of copper gluconate, zinc gluconate, and magnesium aspartate.

Benefits of Sepitonic® M3

The mineral complex in Sepitonic® M3 acts at the mitochondrial level as a “chrono-energizing” and antioxidant agent. According to studies conducted by the company that developed this product, after just 2 hours of application, skin oxygenation increases by nearly 10%, boosting cellular respiration. In the long term, a 28-day clinical study on 30 volunteers revealed that 76% experienced visible effects: deep wrinkles were reduced by around 7% and skin texture improved by approximately 5%.

Among its mechanisms of action are:

  • It stimulates cellular metabolism and energy production in the mitochondria.
  • It protects against oxidative stress: it fights free radicals and reduces protein glycation (a process linked to wrinkle formation).
  • Cellular revitalization: it helps regenerate tissues, maintaining skin firmness. It revitalizes cellular metabolism for optimal regeneration, protects cells against oxidative stress, and participates in the reconstruction of the collagen matrix.
  • Anti-glycation effect: by preventing the attachment of sugars to dermal proteins, it helps delay skin aging.

And its proven benefits are:

  • It increases skin oxygenation (+10 in a few hours).
  • It stimulates cellular energy production (chrono-energizing effect).
  • Antioxidant action: protects cells from oxidative damage.
  • Improves skin texture and visibly reduces wrinkles (–7% deep wrinkles in 28 days).

What is Sepitonic® M3 used for?

It is used as an ingredient in cosmetic and aesthetic medicine products due to its energizing and antioxidant properties. It is designed for skin and hair care. Its main applications include anti-wrinkle, moisturizing, and revitalizing facial creams and serums, as well as post-procedure treatments (such as soothing lotions after peels or laser treatments). It is also used in hair care formulations (shampoos, masks, or lotions) to tone the scalp. In general, it is incorporated into “energy skin care” or anti-oxidative stress products, where it helps stimulate cellular vitality.

Some common practical applications include:

  • Anti-aging facial creams and serums: eye contours, nourishing day/night creams with a revitalizing effect.
  • Post-peeling or post-shaving treatments: soothing lotions or gels that accelerate skin regeneration.
  • Energizing serums and ampoules: liquid concentrates for tired skin.
  • Hair care products: energizing tonics or masks to strengthen the scalp.

For example, it is commonly used in cosmetic formulations for its protective and revitalizing action. In our case, we use Sepitonic® M3 as an ingredient in the specific product for transdermal electroporation, Eye Care, aimed at eye contour care, with the goal of improving dehydrated skin and preventing premature aging.

Applications in treatments and cosmetics

For all the above reasons, it is incorporated into numerous professional formulation and over-the-counter cosmetic products. It can be found in energizing moisturizers, anti-aging serums, revitalizing ampoules, after-sun or post-laser lotions, and toning hair treatments:

  • Anti-aging facial creams: with ingredients such as peptides, hyaluronic acid, or other actives, where it provides oxygenation and cellular energy.
  • Energizing serums and ampoules: liquid concentrates (drops or ampoules) for dull skin.
  • Post-treatment care: soothing formulas to accelerate regeneration after peels, lasers, or other medical-aesthetic treatments.
  • Hair cosmetics: anti-hair loss and strengthening ampoules or shampoos that improve scalp health.

Commitment to quality

This text about Sepitonic M3 has been prepared by professional writers. In addition, we have relied on experts in medicine, engineering and aesthetics as a source of information, as well as specific studies to maintain the quality of what we publish.

At Sisneo Bioscience we are committed to publish truthful and contrasted information. And to update or correct it as soon as new knowledge becomes available.

Among others, we have used the following sources:

    • Cosmetics Design Europe. (2015, February 10). SEPPIC study shows efficacy of Sepitonic M3 to increase cutaneous oxygenation. Cosmetics Design Europe. https://www.cosmeticsdesign-europe.com/Article/2015/02/10/SEPPIC-study-shows-efficacy-of-Sepitonic-M3-to-increase-cutaneous-oxygenation