Eyeliss®

Eyeliss is a cosmetic active specifically designed to target signs of fatigue and aging, which appear as puffiness, under-eye bags, and loss of firmness around the eye contour.

What is Eyeliss?

It is an aqueous functional complex composed of three key actives:

  • Hesperidin methyl chalcone – strengthens capillaries and reduces their permeability.
  • Dipeptide-2 (Val-Trp) – stimulates lymphatic microcirculation.
  • Palmitoyl Tetrapeptide-7 (Pal-GQPR) – improves firmness and elasticity, and reduces mild inflammation.

These ingredients work in synergy, holistically addressing puffiness, vascular fragility, fluid retention, and loss of tone.

  • Decongests: promotes lymphatic drainage and reduces fluid accumulation, thereby relieving under-eye puffiness.
  • Repairs microcirculation: strengthens capillaries and reduces blood leakage that leads to dark circles.
  • Strengthens and smooths: increases skin firmness and elasticity, helping to soften fine wrinkles and relax swollen tissues.

Although Eyeliss is mainly used in home cosmetics, at Sisneo we have incorporated it for use in protocols with transdermal electroporation. Thanks to this technique, peptides and hesperidin reach deeper layers, which can enhance their decongestant, strengthening, and firming effects without increasing irritation or skin damage.

Commitment to quality

This text about Eyeliss has been prepared by professional writers. In addition, we have relied on experts in medicine, engineering and aesthetics as a source of information, as well as specific studies to maintain the quality of what we publish.

At Sisneo Bioscience we are committed to publish truthful and contrasted information. And to update or correct it as soon as new knowledge becomes available.

Among others, we have used the following sources:

    • Allaert FA. Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease. Int Angiol. 2016 Apr;35(2):111-6. PMID: 26928296.
    • Resende DISP, Ferreira MS, Sousa-Lobo JM, Sousa E, Almeida IF. Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel). 2021 Jul 21;14(8):702. doi: 10.3390/ph14080702. PMID: 34451799; PMCID: PMC8400021.